Both conditions significantly reduce fertility potential, but research has shown that IVA can potentially increase live birth rates in women with POI and DOR from just 5% to up to 20%⁽¹⁾⁽²⁾.
The IVA procedure involves:
- Key-hole surgery to remove a portion of ovarian tissue
- Activating dormant follicles outside the body using specialised techniques and then,
- Re-implanting the rejuvenated tissue into the ovarian bed. Patients are then given hormone therapy to stimulate follicle growth, where eggs can develop.
Prof. Dr. Prasanna Supramaniam, Consultant in Obstetrics & Gynaecology, Fertility Specialist, Subspecialist in Reproductive Medicine, Minimally Invasive Gynaecological Surgeon and Associate Professor at Thomson Fertility, shared, "For women with POI or DOR, fertility struggles often feel like a closed door. IVA is a remarkable scientific step forward, creating opportunities for them to use their own eggs in their journey to parenthood. At Thomson Fertility, we believe it is important to highlight such advancements, so that women know there is hope."
Prof. Dr. Kazuhiro Kawamura, Juntendo University, added, "IVA is the culmination of years of research into ovarian tissue activation. Collaborations with centres like Thomson Fertility in Malaysia ensure that more patients can access and benefit from cutting-edge scientific research as they explore the possibilities in starting a family."
Ms. Lakshmi Menon, CEO of Thomson Fertility, said: "Celebrating life has always been at the heart of what we do. By raising awareness of IVA, we want women who have been told their chances are gone to know there is still hope. For Muslim women especially, being able to use their own eggs is a particularly pivotal opportunity. With over 8,000 IVF babies born from a single facility, Thomson Fertility continues to lead in fertility innovation, patient education and compassionate care—empowering women and couples across Malaysia with every chance to build the families they dream of."
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